The smart Trick of ceesdekker That No One is Discussing

The smart Trick of ceesdekker That No One is Discussing

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Using single-molecule optical and AFM imaging and power-spectroscopy tactics, we seek out to unravel the mechanistic elements of the structure and dynamics of chromosomes. Our investigate passions consist of:

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Dynamics of initiation, termination and reinitiation of DNA translocation with the motor protein EcoR124I

A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola

This yielded a breakthrough. Within just only a few months, we were being capable of evaluate transport through someone one-walled carbon nanotube. Determined by low-temperature experiments by an excellent PhD student in my group, Sander Tans (now a valued colleague and professor at Delft College of Engineering having an active exploration lab at AMOLF in Amsterdam), we showed that carbon nanotubes have been legitimate quantum wires with really extensive (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic behaviour.

Microbiology has only existed for just a century, since we started to research micro-organisms a lot more significantly. I assumed nanobiology was an ideal time period, for the reason that all molecular Organic applicable interactions occur within the nanoscale: a protein is a handful of nanometres in size, DNA is two nm thick.’

We use nanofabricated microfluidic structures to pattern spatial boundaries for bacteria and biomimetic vesicles with reconstituted protein networks which assess the fundamental function of spatial confinement on the molecular and cellular level. Our projects include the following:

Instance (one) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in grey, the rim of the pore is highlighted in purple, along with a 3D rendering of your motion of the DNA rod is exhibited.

Let's say, instead of working with traditional major-down silicon electronics, transistors may be constructed from The underside up utilizing one organic molecules given that the switching factors? This concept, which became The premise of these days’s subject of molecular electronics, initial emerged from the 1970s.

But carbon nanotubes have remained a study topic of considerable desire to lots of. In fact, the outlook on working with carbon nanotubes to create useful gadgets, in locations like radio-frequency electronics, electronic electronics and versatile electronics, stays bright.

FtsZ treadmilling is important for Z-ring condensation and septal constriction initiation in bacterial mobile division

Later on we spoke yet again briefly because Dekker felt that our discussion of his faith promptly turned purely philosophical, Whilst Additionally, it concretely aids him in his get the job done.

Developments in nanotechnology from the nineteen nineties designed setting up Digital equipment from one molecules a risk. Cees Dekker recounts how his workforce established a home-temperature transistor dependant on only one carbon nanotube.

Supercoiling-dependent DNA binding: quantitative modeling and apps to bulk and solitary-molecule experiments

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